Altered osmotic swelling behavior of proteoglycan-depleted bovine articular cartilage using high frequency ultrasound
نویسندگان
چکیده
منابع مشابه
Altered osmotic swelling behavior of proteoglycan-depleted bovine articular cartilage using high frequency ultrasound.
Swelling behavior is an electrochemical mechanical property of articular cartilage. It plays an important role in weight bearing and joint lubrication. In this study, the altered transient and inhomogeneous swelling behavior of the degenerated articular cartilage was observed and quantified in situ using ultrasound. Three groups of bovine patellar articular cartilage samples (n = 10 x 3) were o...
متن کاملOsmotic Swelling Behavior of Bovine Cartilage
Introduction Cartilage is a complex tissue whose extracellular matrix mainly consists of charged proteoglycan (PG) assemblies imbedded in a fibrous collagen network. PGs attract water and repel each other due to their negative charges generating a high swelling pressure. Collagens are proteins that form the fibrillar meshwork providing cartilage with its tensile strength. Cartilage extracellula...
متن کاملContribution of proteoglycan osmotic swelling pressure to the compressive properties of articular cartilage.
The negatively charged proteoglycans (PG) provide compressive resistance to articular cartilage by means of their fixed charge density (FCD) and high osmotic pressure (π(PG)), and the collagen network (CN) provides the restraining forces to counterbalance π(PG). Our objectives in this work were to: 1), account for collagen intrafibrillar water when transforming biochemical measurements into a F...
متن کاملAn ultrasound study of altered hydration behaviour of proteoglycan-degraded articular cartilage
BACKGROUND Articular cartilage is a solid-fluid biphasic material covering the bony ends of articulating joints. Hydration of articular cartilage is important to joint lubrication and weight-wearing. The aims of this study are to measure the altered hydration behaviour of the proteoglycan-degraded articular cartilage using high-frequency ultrasound and then to investigate the effect of proteogl...
متن کاملArticular cartilage degeneration classification by means of high-frequency ultrasound.
CONTEXT To date only single ultrasound parameters were regarded in statistical analyses to characterize osteoarthritic changes in articular cartilage and the potential benefit of using parameter combinations for characterization remains unclear. OBJECTIVE Therefore, the aim of this work was to utilize feature selection and classification of a Mankin subset score (i.e., cartilage surface and c...
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ژورنال
عنوان ژورنال: Physics in Medicine and Biology
سال: 2008
ISSN: 0031-9155,1361-6560
DOI: 10.1088/0031-9155/53/10/006